The Itinerant Angler has been around for awhile, so I'm guessing at least some of you are familiar with it or have heard of the site's owner, Zach Matthews.
This is one of the most informative fly fishing sites out there. The podcasts alone are worth a look. I just listened to the Life as a Guide podcast with Ian Crabtree. Really interesting stuff.
Highly recommended. A link to the site is here.